Is there room to negotiate a contract that is already signed "As Is" after an Inspection ?

Yes! “ As-is” just means You’re accepting the property in its current condition without repairs at the time the contract is signed but it’s still subject to inspection & negotiations for repairs can be made after the inspection during the option period.  Of course this is subject to how the contract is written up. 

Yes, absolutely. On Most “as-is” contracts the buyers agent will negotiate with the sellers agent on items that come up on the home inspection. These negotiations can include sellers credits to the buyers for thousands of dollars; also if the bank appraisal falls short of the contract price then another negotiation is likely to take place. 

I will add though once inspection is passed or waived there isn’t much opportunity for the buyers to renegotiate with the sellers. ( other than the aforementioned appraisal or defects in title or open permits / violations that need to be satisfied prior to title changing hands ). 

absolutely- 

One can always try but it depends on the other party if they will renegotiate.

Typically if there is a safety issue you may be able to negotiate those repairs. Cosmetic repairs should not normally be negotiated with an AS IS addendum

even though you sign an As-is contract your still entitled to a home inspection. If your not happy with your findings you can ask the sellers to reconsider or get out of the deal altogether.

Absolutely! Not for repairs but for price reduction 😊

There is always room to negotiate anything during the option period, but most certainly in the case of safety concerns.  You never know until your realtor inquires on your behalf.

In my opinion. yes, if you are still in the Option Period, you can begin negotiations again or terminate the contract,

We usually work with seller's agent to educate seller, that someone will ask to repair a particular item(s) since it's "defective" or in need of repair...etc....
It shows up on this inspection report, and it is more and likely will show up on another potential buyer's...and buyers are buyers, they all will try to leverage one thing or another to reduce price. is your seller willing to waste another 10+ days, 20+ days on another buyer and another...this could signal other potential agent/buyer that something is up with this house...inventory is about 4 months... let's play poker :). 
I haven't encountered one what there's  no mutual agreement. 
it takes seller's agent and buyer's agent to educate seller to not over do it and to buyer as well.